Jochemsen, Aart G.: search on Z-Library

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1

WT1 proteins: functions in growth and differentiation

Volkher Scharnhorst, Alex J van der Eb, Aart G Jochemsen

Journal:

Year:

2001

Language:

english

File:

PDF, 290 KB

english, 2001

2

p53: A Guide to Apoptosis

Meulmeester, Erik, Jochemsen, Aart

Journal:

Current Cancer Drug Targets

Year:

2008

Language:

english

File:

PDF, 426 KB

english, 2008

3

MDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblasts

Gentiletti, Francesca, Mancini, Francesca, D'Angelo, Marco, Sacchi, Ada, Pontecorvi, Alfredo, Jochemsen, Aart G, Moretti, Fabiola

Journal:

Year:

2002

Language:

english

File:

PDF, 347 KB

english, 2002

4

Protein synthesis during chloroplast development in Spirodela oligorhiza : Coordinated synthesis of chloroplast-encoded and nuclear-encoded subunits of ATPase and ribulose-1,5-bisphosphate carboxylase

Hans T. De HEIJ, Aart-Gerrit JOCHEMSEN, Peter Th. J. WILLEMSEN, Gert S. P. GROOT

Journal:

Year:

1984

Language:

english

File:

PDF, 839 KB

english, 1984

5

The clinical development of p53-reactivating drugs in sarcomas – charting future therapeutic approaches and understanding the clinical molecular toxicology of Nutlins

Biswas, Swethajit, Killick, Emma, Jochemsen, Aart G, Lunec, John

Journal:

Expert Opinion on Investigational Drugs

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

6

Loss of HAUSP-Mediated Deubiquitination Contributes to DNA Damage-Induced Destabilization of Hdmx and Hdm2

Erik Meulmeester, Madelon M. Maurice, Chris Boutell, Amina F.A.S. Teunisse, Huib Ovaa, Tsion E. Abraham, Roeland W. Dirks, Aart G. Jochemsen

Journal:

Year:

2005

Language:

english

File:

PDF, 547 KB

english, 2005

7

Microarray-based identification of age-dependent differences in gene expression of human dermal fibroblasts

Dekker, Pim, Gunn, David, McBryan, Tony, Dirks, Roeland W., van Heemst, Diana, Lim, Fei-Ling, Jochemsen, Aart G., Verlaan-de Vries, Matty, Nagel, Julia, Adams, Peter D., Tanke, Hans J., Westendorp, Ru

Journal:

Mechanisms of Ageing and Development

Year:

2012

Language:

english

File:

PDF, 687 KB

english, 2012

8

Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms

Stad, Robert, Little, Natalie A, Xirodimas, Dimitris P, Frenk, Ruth, van der Eb, Alex J, Lane, David P, Saville, Mark K, Jochemsen, Aart G

Journal:

Year:

2001

Language:

english

File:

PDF, 683 KB

english, 2001

9

ATM-Mediated Phosphorylations Inhibit Mdmx/Mdm2 Stabilization by HAUSP in Favor of p53 Activation

Meulmeester, Erik, Pereg, Yaron, Shiloh, Yosef, Jochemsen, Aart G.

Journal:

Year:

2005

Language:

english

File:

PDF, 579 KB

english, 2005

10

Cytoplasmic tethering is involved in synergistic inhibition of p53 by Mdmx and Mdm2

Chihiro Ohtsubo, Daisuke Shiokawa, Masami Kodama, Christian Gaiddon, Hitoshi Nakagama, Aart G. Jochemsen, Yoichi Taya, Koji Okamoto

Journal:

Year:

2009

Language:

english

File:

PDF, 3.57 MB

english, 2009

11

Differential sensitivity to Ad5 E1B-21kD and Bcl-2 proteins of apoptin-induced versus p53-induced apoptosis

Zhuang, Shi-Mei, Shvarts, Avi, Jochemsen, Aart G., van Oorschot, Astrid A.A.M., van der Eb, Alex J., Noteborn, Mathieu H.M.

Journal:

Year:

1995

Language:

english

File:

PDF, 5.07 MB

english, 1995

12

Combined inhibition of CDK and HDAC as a promising therapeutic strategy for both cutaneous and uveal metastatic melanoma

Heijkants, Renier, Willekens, Karen, Schoonderwoerd, Mark, Teunisse, Amina, Nieveen, Maaike, Radaelli, Enrico, Hawinkels, Luuk, Marine, Jean-Christophe, Jochemsen, Aart

Journal:

Year:

2018

Language:

english

File:

PDF, 6.96 MB

english, 2018

13

Mdm4 supports DNA replication in a p53-independent fashion

Wohlberedt, Kai, Klusmann, Ina, Derevyanko, Polina K., Henningsen, Kester, Choo, Josephine Ann Mun Yee, Manzini, Valentina, Magerhans, Anna, Giansanti, Celeste, Eischen, Christine M., Jochemsen, Aart

Journal:

Year:

2020

File:

PDF, 3.25 MB

2020

14

Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice

Lianne S.M. Boesten, A. Susanne M. Zadelaar, Anita van Nieuwkoop, Lihui Hu, Amina F.A.S. Teunisse, Aart G. Jochemsen, Bastiaan Evers, Bob van de Water, Marion J.J. Gijbels, Bart J.M. van Vlijmen, Loui

Journal:

Atherosclerosis

Year:

2009

Language:

english

File:

PDF, 634 KB

english, 2009

15

Activation of cAMP Signaling Interferes with Stress-Induced p53 Accumulation in ALL-Derived Cells by Promoting the Interaction between p53 and HDM2

Naderi, Elin Hallan, Jochemsen, Aart G, Blomhoff, Heidi Kiil, Naderi, Soheil

Journal:

Year:

2011

Language:

english

File:

PDF, 957 KB

english, 2011

16

Modeling of Human Uveal Melanoma in Zebrafish Xenograft Embryos

van der Ent, Wietske, Burrello, Claudia, Teunisse, Amina F. A. S., Ksander, Bruce R., van der Velden, Pieter A., Jager, Martine J., Jochemsen, Aart G., Snaar-Jagalska, B. Ewa

Journal:

Investigative Opthalmology & Visual Science

Year:

2014

Language:

english

File:

PDF, 1.09 MB

english, 2014

17

Mdmx and Mdm2: Brothers in Arms?

Marine, Jean-Christophe, Jochemsen, Aart G.

Journal:

Year:

2004

Language:

english

File:

PDF, 345 KB

english, 2004

18

Hdmx and Mdm2 can repress transcription activation by p53 but not by p63

Little, Natalie A, Jochemsen, Aart G

Journal:

Year:

2001

Language:

english

File:

PDF, 212 KB

english, 2001

19

Wild-type p53 inhibits pro-invasive properties of TGF-β3 in breast cancer, in part through regulation of EPHB2, a new TGF-β target gene

Lam, Suzanne, Wiercinska, Eliza, Teunisse, Amina F. A. S., Lodder, Kirsten, ten Dijke, Peter, Jochemsen, Aart G.

Journal:

Breast Cancer Research and Treatment

Year:

2014

Language:

english

File:

PDF, 2.46 MB

english, 2014

20

A novel germline variant in the DOT1L gene co-segregating in a Dutch family with a history of melanoma

Salgado, Catarina, Kwesi-Maliepaard, Eliza Mari, Jochemsen, Aart G., Visser, Mijke, Harland, Mark, van Leeuwen, Fred, van Doorn, Remco, Gruis, Nelleke

Journal:

Melanoma Research

Year:

2019

File:

PDF, 375 KB

2019

21

Loss of HAUSP-Mediated Deubiquitination Contributes to DNA Damage-Induced Destabilization of Hdmx and Hdm2

Erik Meulmeester, Madelon M. Maurice, Chris Boutell, Amina F.A.S. Teunisse, Huib Ovaa, Tsion E. Abraham, Roeland W. Dirks, Aart G. Jochemsen

Journal:

Year:

2005

Language:

english

File:

PDF, 91 KB

english, 2005

22

Loss of BAP1 Is Associated with Upregulation of the NFkB Pathway and Increased HLA Class I Expression in Uveal Melanoma

Souri, Zahra, Wierenga, Annemijn P. A., van Weeghel, Christiaan, van der Velden, Pieter A., Kroes, Wilma G. M., Luyten, Gregorius P. M., van der Burg, Sjoerd H., Jochemsen, Aart G., Jager, Martine J.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.34 MB

english, 2019

23

Molecular and functional analysis of the XPBC/ERCC-3 promoter: transcription activity is dependent on the integrity of an Sp1-binding site

Ma, Libin, Weeda, Geert, Jochemsen, Aart.G., Bootsma, Dirk, Hoeijmakers, Jan H.J., van der Eb, Alex J.

Journal:

Nucleic Acids Research

Year:

1992

Language:

english

File:

PDF, 8.03 MB

english, 1992

24

Distinct p53-independent apoptotic cell death signalling pathways in testicular germ cell tumour cell lines

Herman Burger, Kees Nooter, Antonius W.M. Boersma, Kyra E. van Wingerden, Leendert H.J. Looijenga, Aart G. Jochemsen, Gerrit Stoter

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 147 KB

english, 1999

25

10.1038/ng714

Parant, John, Chavez-Reyes, Arturo, Little, Natalie A., Yan, Wen, Reinke, Valerie, Jochemsen, Aart G., Lozano, Guillermina

Journal:

Nature Genetics

Year:

2001

Language:

english

File:

PDF, 3.71 MB

english, 2001

26

Mdmx as an essential regulator of p53 activity

Jean-Christophe Marine, Aart G. Jochemsen

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 806 KB

english, 2005

27

USP10: Friend and Foe

Aart G. Jochemsen, Yosef Shiloh

Journal:

Year:

2010

Language:

english

File:

PDF, 603 KB

english, 2010

28

Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53

van der Ent, Wietske, Jochemsen, Aart G, Teunisse, Amina FAS, Krens, SF Gabriel, Szuhai, Karoly, Spaink, Herman P, Hogendoorn, Pancras CW, Snaar-Jagalska, B Ewa

Journal:

The Journal of Pathology

Year:

2014

Language:

english

File:

PDF, 1.81 MB

english, 2014

29

Functions of MDMX in the Modulation of the p53-Response

Lenos, Kristiaan, Jochemsen, Aart G.

Journal:

Journal of Biomedicine and Biotechnology

Year:

2011

Language:

english

File:

PDF, 1.47 MB

english, 2011

30

Distinct Regulation of p53 and p73 Activity by Adenovirus E1A, E1B, and E4orf6 Proteins

Steegenga, Wilma T., Shvarts, Avi, Riteco, Nicole, Bos, Johannes L., Jochemsen, Aart G.

Journal:

Molecular and Cellular Biology

Year:

1999

Language:

english

File:

PDF, 1.68 MB

english, 1999

31

p63

Natalie A Little, Aart G Jochemsen

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2002

Language:

english

File:

PDF, 85 KB

english, 2002

32

Preclinical evaluation of drug combinations identifies co-inhibition of Bcl-2/XL/W and MDM2 as a potential therapy in uveal melanoma

Decaudin, Didier, Frisch Dit Leitz, Estelle, Nemati, Fariba, Tarin, Malcy, Naguez, Adnan, Zerara, Mohamed, Marande, Benjamin, Vivet-Noguer, Raquel, Halilovic, Ensar, Fabre, Claire, Jochemsen, Aart, Ro

Journal:

European Journal of Cancer

Year:

2020

File:

PDF, 2.56 MB

2020

33

Oncogenic functions of hMDMX inin vitrotransformation of primary human fibroblasts and embryonic retinoblasts

Kristiaan Lenos, Job de Lange, Amina FAS Teunisse, Kirsten Lodder, Matty Verlaan-de Vries, Eliza Wiercinska, Marja JM van der Burg, Karoly Szuhai, Aart G Jochemsen

Journal:

Molecular Cancer

Year:

2011

Language:

english

File:

PDF, 657 KB

english, 2011

34

EGR-1 enhances tumor growth and modulates the effect of the Wilms' tumor 1 gene products on tumorigenicity

Scharnhorst, Volkher, Menke, Aswin L, Attema, Joline, Haneveld, Johan Klein, Riteco, Nicole, van Steenbrugge, Gert J, van der Eb, Alex J, Jochemsen, Aart G

Journal:

Year:

2000

Language:

english

File:

PDF, 554 KB

english, 2000

35

Synthetic lethality between Rb, p53 and Dicer or miR-17–92 in retinal progenitors suppresses retinoblastoma formation

Nittner, David, Lambertz, Irina, Clermont, Frederic, Mestdagh, Pieter, Köhler, Corinna, Nielsen, Søren Jensby, Jochemsen, Aart, Speleman, Frank, Vandesompele, Jo, Dyer, Michael A., Schramm, Alexander,

Journal:

Nature Cell Biology

Year:

2012

Language:

english

File:

PDF, 3.53 MB

english, 2012

36

Repression of the minimal hla-b promoter by c-myc and p53 occurs through independent mechanisms

Marieke Griffioen, Wilma T. Steegenga, Ilse J.M. Ouwerkerk, Lucy T.C. Peltenburg, Aart G. Jochemsen, Peter I. Schrier

Journal:

Molecular Immunology

Year:

1998

Language:

english

File:

PDF, 1.39 MB

english, 1998

37

MDMX (MDM4), a Promising Target for p53 Reactivation Therapy and Beyond

Marine, Jean-Christophe, Jochemsen, Aart G.

Journal:

Cold Spring Harbor Perspectives in Medicine

Year:

2016

Language:

english

File:

PDF, 949 KB

english, 2016

38

Functional Analyses of a Human Vascular Tumor FOS Variant Identify a Novel Degradation Mechanism and a link to Tumorigenesis

van Ijzendoorn, David G.P, Forghany, Zary, Liebelt, Frauke, Vertegaal, Alfred C., Jochemsen, Aart G., Bovée, Judith V.M.G, Szuhai, Karoly, Baker, David A.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 2.62 MB

english, 2017

39

Selective PKCδ inhibitor B106 elicits uveal melanoma growth inhibitory effects independent of activated PKC isoforms

Heijkants, Renier, Teunisse, Amina, de Vries, Jelle, Ovaa, Huib, Jochemsen, Aart

Journal:

ACS Chemical Biology

Year:

2018

Language:

english

File:

PDF, 1013 KB

english, 2018

40

Increased Radioresistance and Accelerated B Cell Lymphomas in Mice with Mdmx Mutations that Prevent Modifications by DNA-Damage-Activated Kinases

Yunyuan V. Wang, Mathias Leblanc, Mark Wade, Aart G. Jochemsen, Geoffrey M. Wahl

Journal:

Year:

2009

Language:

english

File:

PDF, 1.26 MB

english, 2009

41

Central chondrosarcoma progression is associated with pRb pathway alterations: CDK4 down-regulation and p16 overexpression inhibit cell growth in vitro

Yvonne M. Schrage, Suzanne Lam, Aart G. Jochemsen, Anne-Marie Cleton-Jansen, Antonie H.M. Taminiau, Pancras C.W. Hogendoorn, Judith V.M.G. Bovée

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 982 KB

english, 2009

42

Macrophage P53 controls foam cell death in atherosclerotic lesions of apolipoprotein E deficient mice

Marion J.J. Gijbels, Lianne S.M. Boesten, A. Suzanne M. Zadelaar, Aart G. Jochemsen, Bob van de Water, Bart J.M. van Vlijmen, Louis M. Havekes, Menno P.J. de Winther

Journal:

Vascular Pharmacology

Year:

2006

Language:

english

File:

PDF, 52 KB

english, 2006

43

Reactivation of p53 as therapeutic intervention for malignant melanoma

Jochemsen, Aart G.

Journal:

Current Opinion in Oncology

Year:

2014

Language:

english

File:

PDF, 327 KB

english, 2014

44

Mdmx: A p53 activator?

Jochemsen, Aart G.

Journal:

Year:

2012

Language:

english

File:

PDF, 787 KB

english, 2012

45

Mutational Analysis of Fibrillarin and Its Mobility in Living Human Cells

Sabine Snaar, Karien Wiesmeijer, Aart G. Jochemsen, Hans J. Tanke and Roeland W. Dirks

Journal:

The Journal of Cell Biology

Year:

2000

Language:

english

File:

PDF, 2.56 MB

english, 2000

46

Embryonic Zebrafish: Different Phenotypes after Injection of Human Uveal Melanoma Cells

van der Ent, Wietske, Burrello, Claudia, de Lange, Mark J., van der Velden, Pieter A., Jochemsen, Aart G., Jager, Martine J., Snaar-Jagalska, B. Ewa

Journal:

Ocular Oncology and Pathology

Year:

2015

Language:

english

File:

PDF, 828 KB

english, 2015

47

Comparative study of the p53-mdm2 and p53-MDMX interfaces

Böttger, Volker, Böttger, Angelika, Garcia-Echeverria, Carlos, Ramos, Yolande FM, van der Eb, Alex J, Jochemsen, Aart G, Lane, David P

Journal:

Year:

1999

Language:

english

File:

PDF, 450 KB

english, 1999

48

NEK11 as a candidate high-penetrance melanoma susceptibility gene

Christodoulou, Eirini, van Doorn, Remco, Visser, Mijke, Teunisse, Amina, Versluis, Mieke, van der Velden, Pieter, Hayward, Nicholas K, Jochemsen, Aart, Gruis, Nelleke

Journal:

Journal of Medical Genetics

Year:

2019

File:

PDF, 929 KB

2019

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